Aiyuk on the PUP with a knee issue; Week 2 status uncertain, complicating SF’s WR mix and target projections.

Aiyuk’s role becomes pivotal as SF navigates injury issues; his big‐play ability could buoy the offense while Kittle is sidelined, with Purdy targeting him more in intermediate and vertical routes.

Brandon Aiyuk remains SF’s top pass-game option. Bourne’s signing adds depth but should not threaten Aiyuk’s target share. SF’s WR rotation becomes more flexible, allowing Aiyuk to operate from multiple alignments while Bourne and Pearsall supplement the short-to-intermediate game.

Aiyuk heads into a week with a knee issue, relying on Bourne to stabilize depth. Bourne’s veteran presence should allow SF to manage Aiyuk’s workload while keeping the offense efficient. If Bourne steps in quickly, Aiyuk’s target ceiling stays high but could see a momentary dip in early games as SF tests depth.

Aiyuk is listed on the PUP, creating a vacancy opposite Bourne. His status will largely define how SF deploys the WR corps. If Aiyuk is sidelined, Bourne steps in as a primary outside target, with Pearsall and Watkins absorbing additional roles and the rest filling in behind them as SF maintains a balanced attack.